Constructional Selection, Methylation and Adaptable Representation: Preliminary Findings
نویسنده
چکیده
This paper investigates the adaptability of genotypes produced by a modified genome growth algorithm (MGG) in a genetic algorithm. MGG uses constructional selection, a genome growth strategy modeled on the evolution of the biological genome [1]. Experiments did not favor the more costly MGG genotypes. This paper also proposes a new type of mutation operator: meth, which is loosely based on DNA methylation. Experiments suggest the utility of ‘methylation’ to improve the adaptability of representations and to build robust and adaptable digital structures.
منابع مشابه
A preliminary study of the association between the ABCA1 gene promoter DNA methylation and coronary artery disease risk
Coronary artery disease (CAD) is a common health problem in Iranian population. ATP binding cassette transporter A1 (ABCA1) plays central role in the efflux of the cholesterol from peripheral tissues back to liver. Inactivation of ABCA1 by epigenetic change such as DNA methylation may contribute to the development of CAD. The present study investigated the association between promoter DNA methy...
متن کاملEmotion in lexicon and grammar: lexical-constructional interface of Mandarin emotional predicates
The unique behaviors of emotional (or psychological) predicates have long been studied as a central issue in developing theoretical accounts for the interaction of lexical semantics and argument realization (cf. Talmy, Grammatical categories and the lexicon, 1985; Talmy, Typology and process in concept structuring, 2000; Croft, Surface subject choice of mental verbs, 1986; Dowty, Language 67: 5...
متن کاملTowards an evolutionary-developmental approach for real-world substrates
Extending “body-brain” evolution to the real-world presents a number of difficulties due to conflicting idealizations between evolutionary and constructional models. Toward addressing this gap, we develop a simple model system to analyze the effects of undoing these idealizations. Preliminary experiments with this system show that high variability developmental substrates can influence evolutio...
متن کاملGene Expression and Promoter Methylation Status of VHL, Runx-3, E-cadherin, P15 and P16 Genes During EPO-Mediated Erythroid Differentiation of CD34+ Hematopoietic Stem Cells
Background: VHL (von Hippel-Lindau), Runx-3 (Runt-related transcription factor 3), E-cadherin (Epithelial cadherin), P15 (INK4a, cyclin dependent kinase inhibitor), and P16 (INK4b) genes are essential in hematopoiesis. The aim of this study was to explore the correlation between gene expression and promoter methylation in CD34+ stem cells before and after differentiation to erythroid lineage. M...
متن کاملAn Enhanced Weighted Graph Model for Examination/Course Timetabling
We introduce an enhanced weighted graph model whose vertices and edges have several attributes that make it adaptable to a variety of examination and course timetabling scenarios. In addition, some new vertexand colour-selection heuristics arise naturally from this model, and our implementation allows for the use and manipulation of various combinations of them along with or separate from the c...
متن کامل